As Vice President and Head of Translational Science & 实验医学 for 心血管,肾脏和代谢 (CVRM), 我负责澳门第一赌城在线娱乐的人类目标验证, biomarker and precision medicine departments, working closely with team leaders in both early and late CVRM研究. I help to direct our early-stage research priorities in CVRM and am involved in a multitude of initiatives across our early CVRM portfolio.

Our team’s collective ambition is to stop, 反向, 有一天, cure CRVM diseases by delivering innovative, life-changing medicines and solutions to patients. Across our departments, patients are always the starting point of our work. 为此目的, the foundation of our research relies heavily on human clinical data and biological samples, rather than cellular or animal modelling.

I completed my PhD and MD at the University of 剑桥, Departments of Clinical Biochemistry and Medicine and am currently a practicing endocrinologist. The time I spend with patients shapes my understanding of their needs as well as the gaps they experience in existing healthcare systems. This is both rewarding and incredibly valuable to the work I do each day at 澳门在线赌城娱乐.

Working across industry and applied medicine, a key priority for me as department head is ensuring we have a clear purpose as a team. I encourage open communication of priorities to foster a collaborative and stimulating work environment where we can work together to push the boundaries of science to deliver life-changing medicines to our patients.


As a full-time consultant, I was not able to conduct the research that I was passionate about. What attracted me to 澳门在线赌城娱乐 was the breadth and depth of their research programmes, 特别是在crvrm疾病中. My role now allows me to be at the forefront of cutting-edge clinical research, while still seeing patients as a practicing clinician; it’s both exciting and fulfilling.

本杯状 Vice President and Head of Translational Science & 实验医学, 心血管,肾脏和代谢 (CVRM), 澳门在线赌城娱乐

本杯状, VP and Head of Department, Translational Science & 实验医学

电流的作用

Vice President and Head of Department of Translational Science & 实验医学 (TSEM), 心血管,肾脏和代谢 (CVRM)

2021年至今

Executive Director and Head of Department of 心血管,肾脏和代谢 (CVRM) Translational Science & 实验医学(TESM), 澳门在线赌城娱乐; driving strategy, objectives and delivery of the TSEM programme. Responsible for human target validation, biomarker and precision medicine strategies for early CVRM projects.

2019 – 2021

主任医师 & Team Lead 实验医学, Translational Science & 实验医学, 早期CVRM, 澳门在线赌城娱乐, 制定战略, objectives and delivery of the experimental medicine programme.

2016 – 2019

主任医师, 临床发现组, 早期临床开发, 澳门在线赌城娱乐, acted as lead for 实验医学 collaboration with the University of 剑桥, and drove clinical development programme for A1AT therapeutic gene editing project. Study Physician in 肿瘤学 (ATM (Ph2 clinical trial); DNA-PK (Preparation of IND submission to FDA & 临床研究设计).

2016年至今

内分泌学家名誉顾问 & Internal Medicine Physician, 剑桥 University Hospital Foundation Trust

科学出版物

Effects of protein-coding variants on blood metabolite measurements and clinical biomarkers in the UK Biobank

唠叨了., Dhindsa R.S.米德尔顿·L. 等. 我是热内吗. 2023 Feb 10:S0002-9297(23)00046-0. doi: 10.1016/j.ajhg.2023.02.002.

Human genetics uncovers MAP3K15 as an obesity-independent therapeutic target for diabetes

唠叨了., Dhindsa R.S.米切尔·J. 等. Sci副词. 2022年11月18日;8(46):eadd5430. doi: 10.1126 / sciadv.add5430.

Rare variant contribution to human disease in 281,104 UK Biobank exomes

王问., Dhindsa R.S.,卡斯·K. 等. 自然. 2021年9月,597 (7877):527 - 532. doi: 10.1038/s41586-021-03855-y.

HEROIC: a 5-year observational cohort study aimed at identifying novel factors that drive diabetic kidney disease: rationale and study protocol

McCafferty K, Caplin B, Knight S 等. BMJ开放. 2020;10:e033923. doi: 10.1136 / bmjopen - 2019 - 033923


Veeva ID: Z4-54154
编制日期:2023年4月